- Type: Cartilage
- Source: Fish
- Color: White
- Ingredients: Salmon Collagen Proteoglycan Powder
- Packaging: Food Grade Plastics Bag
- Place of Origin: Japan
Packaging & Delivery
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SpecificationsSalmon Collagen Proteoglycan Complex contains 30% proteoglycan and 40% type-II collagen.
Salmon Collagen Proteoglycan Complex contains 30% proteoglycan and 40% type-II collagen. It has effect on joint pain as well as on skin beauty.
For Joint Pain
Main component in Articular Cartilage
Articular cartilage is the bluish gel-like tissue that covers the ends of bones. It is 4~6cm thick, softer than bone, and could be found on many joint surfaces. The type II collagen is the basis for articular cartilage, and its fibrillar network allows cartilage to entrap the proteoglycan aggregate. The synovial fluid, which is also a part of the articular cartilage, contains hyaluronic acid as its main component, lubricates the articulating joints. The articular cartilage makes joints easier to move, and allows the bones to glide over each other with very little friction.
For Skin Care
The proteoglycan exists in the extracellular matrix or the surface of cells of animals, forms complex by combining itself with the protein matrix in fiber, such as hyaluronic acid or collagen.
Skin Rejuvenation Test
Fibroblasts and the proteoglycan sample manufactured by Linise were used to measure the enhancement effect on the production of collagen & hyaluronic acid, and also to testify the effect on cellular activation.
The corium is composed of collagen and hyaluronic acid. Collagen constitutes 70% of the corium, and its function is to create resilience and elasticity for skin. Hyaluronic acid is known for its moisturizing effect; it protect skin from losing elasticity and water.
The collagen and hyaluronic acid in skin decrease with age, and cause skin problems such as wrinkles, sagging skin, declination of elasticity as well as moisture retention ability. Due to the fact that the collagen and hyaluronic acid is produced in fibroblast, therefore, the material that can activate the fibroblast, stimulating the production of collagen and hyaluronic acid would be effective on skin beauty.
TNF-α Production Inhibiting Test
The ELISA method was used to measure the inhibiting effect of the production of TNF-α, which was stimulated with the lipopolysaccharide (LPS), in the microphage cell line (J774.1) of mice.
Inflammatory cells such as macrophage would produce inflammatory cytokine (TNF-α) if they accept the stimulation from LPS. The TNF-α will differentiate the osteoblast into osteoclast, causing osteoporosis or rheumatoid arthritis; meanwhile, the TNF-α in liver will be the cause of liver dysfunction or necrosis and eventually result in hepatic insufficiency or cirrhosis. Thus, the inhabitation of the TNF-α production could have effect on preventing inflammation, osteoporosis, rheumatoid arthritis or hepatic dysfunction.
(The recommended daily intake is15~30mg.)